Malaria is caused by Plasmodium parasites, which are transmitted through the bites of infected female Anopheles mosquitoes. On the other hand, culicine mosquitoes(Aedes, Culex, and Mansonia mosquito) can be important vectors for human pathogens and feed on humans like the Anopheles mosquito. For this reason, it raises the question of Why Aedes aegypti is not a malaria vector. The previous report showed that the plasmodium parasite does not successfully develop and transmit in Aedes or culicine mosquitoes. Even found an Aedes mosquito in the Malaria endemic area. The fact that Aedes mosquitoes are not able to pass the Plasmodium parasite like Anopheles mosquitoes. Because the factors and immune response in the Aedes mosquito (culicine mosquito) are too strong and play a crucial role to makes the Plasmodium parasites have poor adaptation to new disease vectors(factors beneficial to the host). In addition, the Aedes immune response can not influence the plasmodium parasite to survive in their body(the gut) and prevent the transmission of the human-infectious Plasmodium parasite.

Vanutsarin Khongsrisak ID: 6536456